Guides
Omega-3 Fatty Acids & Brain Health: What the Research Actually Shows
DHA, EPA, and the brain — the MIDAS trial, meta-analyses on cognitive decline, dosing for neuroprotection, and how to choose a quality supplement.
Guides & Articles
Guides
Microdosing Psychedelics for Cognitive Enhancement: What the Science Really Says
Sub-perceptual doses of psilocybin and LSD for focus and creativity — the 2025 meta-analysis, placebo-controlled trial results, and an honest assessment of the evidence.
Guides
tDCS Brain Stimulation: Do Consumer Neurostimulators Actually Work?
Transcranial direct current stimulation for cognitive enhancement — the December 2025 FDA approval, clinical evidence for working memory, consumer devices, and realistic expectations.
Guides
The Beginner's Guide to Smart Drugs: Where to Start
New to cognitive enhancement? This guide cuts through the hype — what nootropics can realistically do, which compounds are worth researching, and how to approach self-experimentation safely.
Nootropics
Noopept: The Most Potent Peptide-Derived Nootropic
1,000× more potent than piracetam by weight, Noopept upregulates NGF and BDNF — here's what the research actually shows, plus optimal dosing and choline stacking.
ADHD
Modafinil for ADHD: Does It Work? Evidence, Dosing & Alternatives
Modafinil isn't FDA-approved for ADHD, but three RCTs show it works. We examine the evidence, compare it to Adderall and Strattera, and explain who benefits most.
Racetams
Phenylpiracetam: The Stimulant Racetam Guide
The only nootropic banned from Olympic competition. 20–60× more potent than piracetam, fast-acting, and stimulating — but requires strict cycling due to rapid tolerance.
Modafinil
Modafinil: Mechanism, Dosing & Cognitive Effects
A deep dive into how modafinil works, what the research says about its cognitive effects, optimal dosing strategies, and how to stack it responsibly.
ADHD Meds
Atomoxetine for Cognitive Enhancement: The Off-Label Guide
Atomoxetine (Strattera) is an ADHD medication with a uniquely clean profile — no stimulant classification, no dopamine flooding. Here's what it actually does and who it suits.
Racetams
Piracetam: The Original Nootropic, 50 Years On
Piracetam was synthesized in 1964 and literally gave us the word "nootropic." Half a century later, what does the evidence actually show? And why does everyone stack it with choline?
Stacks
Nootropic Stacks: The Evidence-Based Combinations That Work
Popular nootropic combinations — from modafinil + piracetam to caffeine + L-theanine — ranked by evidence quality. What synergises, what cancels out, and what's just placebo.
Adaptogens
Ashwagandha vs Rhodiola: Which Adaptogen Should You Take?
Both reduce stress — but they work through completely different mechanisms and suit very different people. Here's the direct comparison that tells you which one to choose.
Stacks
Alpha-GPC vs Citicoline: Which Choline Source is Better?
Both deliver choline to the brain, but they differ in bioavailability, additional effects, and best use cases. The evidence-based comparison for nootropic users and racetam stackers.
Racetams
Racetam Comparison: Which One Is Right for You?
Piracetam, aniracetam, oxiracetam, pramiracetam, phenylpiracetam — same chemical family, very different characters. This guide maps each to the goals it actually suits.
Guides
Best Nootropics for Studying: What Actually Works
Ranked by evidence: what to take before a study session, what builds over time, and what to avoid before exams. A practical protocol from prep to exam week.
Modafinil
Modafinil vs Atomoxetine: Two Different Paths to the Same Desk
Both are used off-label for cognitive enhancement — but they work through completely different mechanisms, suit different problems, and fail in different ways. The comparison most guides get wrong.
Stacks
Piracetam + Alpha-GPC: The Original Nootropic Stack, Explained
Why piracetam requires choline, how Alpha-GPC became the standard pairing, the protocol that actually works, and what the combination does to the brain — mechanistically explained.
Guides
Nootropics for Women: What the Research Actually Shows
Most nootropics research used male subjects. Sex differences in metabolism, hormonal cycling, and neurotransmitter baselines mean the standard advice doesn't always apply. Here's what the evidence says.
Stacks
Caffeine + L-Theanine: The Most Validated Nootropic Stack
Why combining these two compounds outperforms either alone, what the clinical evidence from randomised trials shows, the optimal ratio, and where it fits alongside prescription nootropics.
Adaptogens
Lion's Mane Mushroom: NGF, Neurogenesis, and the Evidence Behind the Hype
A rigorous look at lion's mane — the nerve growth factor mechanism, what human trials found, why product quality varies enormously, and where it fits in a serious nootropic protocol.
Guides
Magnesium and Cognitive Performance: What the Research Actually Shows
Why the brain suffers first from magnesium deficiency, which forms cross the blood-brain barrier, and what L-threonate evidence says about memory, learning, and neuroprotection.